The following filter criteria for genes differentially expressed were used: PDAC versus normal pancreas (bulk tissue), PDAC versus normal pancreas (microdissected normal ductal cells), and PDAC versus ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

Researchers have discovered that cancer spread isn’t random—it follows a kind of biological “program.” By studying colon ...

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic ...

A newly released publication examines how deuterium concentration may influence gene activity in lung cancer cells. The study ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...

Reply to: Focal Boosting in Localized Prostate Cancer in the Era of Systemic Therapy and Prostate-Specific Membrane Antigen Imaging In the early 20th century, Paul Ehrlich coined the term “magic ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...

Inside a diseased cell, the genes are in chaos. Some are receiving signals to overproduce a protein. Others are reducing ...